Some DNA is so dangerous that it's not compatible with life

Posted on Sunday, Jan 07 2007 @ 19:13 CET by Thomas De Maesschalck
A group of researchers believe there are DNA sequences and chains of amino acids so dangerous to life that they don't exist:
"It's like looking for a needle that's not actually in the haystack," says Greg Hampikian, professor of genetics at Boise State University in Idaho, who is leading the project. "There must be some DNA or protein sequences that are not compatible with life, perhaps because they bind some essential cellular component, for example, and have therefore been selected out of circulation. There may also be some that are lethal in some species, but not others. We're looking for those sequences."

“There must be some DNA or protein sequences that are not compatible with life and have therefore been selected out”To do this, Hampikian and his colleage Tim Anderson, also at Boise, have developed software that calculates all the possible sequences of nucleotides - the "letters" of DNA - up to a certain length, and then scans sequence databases such as the US National Institutes of Health's Genbank to identify the smallest sequences that aren't present. Those that don't occur in one species but do in others are termed "nullomers", while those that aren't found in any species are termed primes.


About the Author

Thomas De Maesschalck

Thomas has been messing with computer since early childhood and firmly believes the Internet is the best thing since sliced bread. Enjoys playing with new tech, is fascinated by science, and passionate about financial markets. When not behind a computer, he can be found with running shoes on or lifting heavy weights in the weight room.



Loading Comments