Instructables user fungus amungus has modded a defunct NES console into a flash memory reader:
The NES consoles and game cartridges have been used for many things, but I wanted to make some ridiculous system that utilized the slide-in action of the system. Of course what made the most sense was to put an 8 gig flash drive in the cartridge and make the NES the port. It had to happen!
And so it did. And here's how it happened.