Just a couple of days after the launch of the AMD Radeon Software Crimson Edition 16.1.1 Hotfix, a new version of this driver has been published to fix an issue with Fallout 4. You can download the driver over here.
 Fallout 4 - Flickering may be experienced at various game locations with the v1.3 game update and with AMD Crossfire™ enabled. The AMD Radeon™ Software Crimson Edition 16.1.1 Hotfix driver has been updated. Please download this driver once again and reinstall it to address this issue.