AMD has been keeping pretty mum about its next Threadripper so we don't know what to expect. If it's based on a full Rome design, the new AMD HEDT platform could feature up to 64 CPU cores, with 4-channel DDR4 and 64 PCIe 4.0 lanes:
The 3rd generation Ryzen Threadripper will likely be a derivative of the company's "Rome" multi-chip module, and compatible with existing socket TR4 motherboards with a BIOS update, although a new chipset could also be launched to enable PCI-Express gen 4.0. AMD has the option to deploy up to 64 CPU cores across eight 7 nm "Zen 2" chiplets, while the 12 nm I/O controller die will be likely reconfigured for the HEDT platform with a monolithic 4-channel DDR4 memory interface and 64 PCIe gen 4.0 lanes. It's capable of 8 memory channels on the 2nd generation EPYC.