Bleeping Computer writes the patches are resulting in DNS resolution issues that prevent access to shared folders on servers when a user tries to access the folder by the server's name. This problem seems to occur primarily on systems with disabled multicase name resolution (LLMNR):
After users began reporting the issue on BleepingComputer's forum, users determined that many affected users are using the Dentrix Dental Practice Management software in their offices.
A longstanding support recommendation for Dentrix customers to reduce network lag has been to disable multicase name resolution (LLMNR) on Windows workstations. This is done by enabling the 'Turn off multicast name resolution' group policy under Computer Configuration > Administrative Templates > Network > DNS Client. -- Bleeping Computer
Gaming problems tooBeta News writes the patches are also linked to video gaming issues. Reported issues include game crashes, performance issues, error messages, screen flickering, etc. Some Windows 10 users are also seen the screen flicker issue when resizing Edge or Chrome browser windows.
As reported by Ghacks, many complaints can be found online in Microsoft's support forum and message boards, with Windows 10 users reporting various problems following the installation of the update. Some people have been plagued by bootloops and error code 0xc000021a after installing KB5001330, while others have encountered problems and error code 0x800f0984 when trying to install the update itself.As is typical, these issues don't occur in every system. Often, it's a combination of certain hardware and driver versions that contribute to at least some of the bugs. Some affected users were able to resolve issues by updating to a newer graphics driver, or rolling back to an earlier version.