As the site reports, the chip starts returning non-random data (when random data is expected) via the RdRand instruction following a suspend/resume cycle.
Referenced is this bug report outlining that the RdRand instruction on an older AMD A6-6310 processor isn't properly behaving following a suspend/resume. By avoiding RdRand usage on the system as part of generating a UUID, the reported systemd issue no longer happens.Interestingly, the issue first got identified in 2014 but it was wrongly diagnosed as a BIOS bug instead of an issue with AMD's CPUs.